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Progression of BRAF-induced thyroid cancer is associated with epithelial-mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling
Mice with thyroid-specific expression of oncogenic BRAF (Tg-Braf) develop papillary thyroid cancers (PTC) that are locally invasive and have well-defined foci of poorly differentiated carcinoma (PDTC). To investigate the PTC-PDTC progression, we performed a microarray analysis using RNA from paired...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136543/ https://ncbi.nlm.nih.gov/pubmed/21383698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.44 |
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