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Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells
Inhibitors of RET, a tyrosine kinase receptor encoded by a gene that is frequently mutated in medullary thyroid cancer, have emerged as promising novel therapies for the disease. Rapalogs and other mammalian target of rapamycin (mTOR) inhibitors are effective agents in patients with gastroenteropanc...
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| Gepubliceerd in: | Endocr Relat Cancer |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375728/ https://ncbi.nlm.nih.gov/pubmed/23828865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0085 |
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