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Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells

Inhibitors of RET, a tyrosine kinase receptor encoded by a gene that is frequently mutated in medullary thyroid cancer, have emerged as promising novel therapies for the disease. Rapalogs and other mammalian target of rapamycin (mTOR) inhibitors are effective agents in patients with gastroenteropanc...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Gild, Matti L, Landa, Iñigo, Ryder, Mabel, Ghossein, Ronald A, Knauf, Jeffrey A, Fagin, James A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375728/
https://ncbi.nlm.nih.gov/pubmed/23828865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-13-0085
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