Coordinate linkage of HIV evolution reveals regions of immunological vulnerability

Cellular immune control of HIV is mediated, in part, by induction of single amino acid mutations that reduce viral fitness, but compensatory mutations limit this effect. Here, we sought to determine if higher order constraints on viral evolution exist, because some coordinately linked combinations o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Dahirel, Vincent, Shekhar, Karthik, Pereyra, Florencia, Miura, Toshiyuki, Artyomov, Mikita, Talsania, Shiv, Allen, Todd M., Altfeld, Marcus, Carrington, Mary, Irvine, Darrell J., Walker, Bruce D., Chakraborty, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136285/
https://ncbi.nlm.nih.gov/pubmed/21690407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105315108
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados