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Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection

Without therapy, most persons infected with the human immunodeficiency virus (HIV) ultimately progress to AIDS. Rare individuals (“elite controllers”) maintain very low levels of HIV RNA without therapy, thereby making disease progression and transmission unlikely. Certain HLA Class I alleles are ma...

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Detalhes bibliográficos
Main Authors: Košmrlj, Andrej, Read, Elizabeth L., Qi, Ying, Allen, Todd M., Altfeld, Marcus, Deeks, Steven G., Pereyra, Florencia, Carrington, Mary, Walker, Bruce D., Chakraborty, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098720/
https://ncbi.nlm.nih.gov/pubmed/20445539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08997
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