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Structural basis for the unfolding of anthrax lethal factor by protective antigen oligomers
The protein transporter, anthrax lethal toxin, is comprised of protective antigen (PA), a transmembrane translocase, and lethal factor (LF), a cytotoxic enzyme. Following assembly into holotoxin complexes, PA forms an oligomeric channel that unfolds LF and translocates it into the host cell. We repo...
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| Hoofdauteurs: | , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3133606/ https://ncbi.nlm.nih.gov/pubmed/21037566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1923 |
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