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Domain flexibility modulates the heterogeneous assembly mechanism of anthrax toxin protective antigen

Individually, the three protein components of anthrax toxin are nontoxic, but when they assemble, they form active holotoxin complexes. The role of the protective antigen (PA) component of the toxin is to deliver the two other enzyme components, lethal factor (LF) and edema factor (EF), across the p...

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Bibliografske podrobnosti
Main Authors: Feld, Geoffrey K., Kintzer, Alexander F., Tang, Iok I, Thoren, Katie L., Krantz, Bryan A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249527/
https://ncbi.nlm.nih.gov/pubmed/22063095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.035
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