Anthrax Toxin Receptor Drives Protective Antigen Oligomerization and Stabilizes the Heptameric and Octameric Oligomer by a Similar Mechanism

BACKGROUND: Anthrax toxin is comprised of protective antigen (PA), lethal factor (LF), and edema factor (EF). These proteins are individually nontoxic; however, when PA assembles with LF and EF, it produces lethal toxin and edema toxin, respectively. Assembly occurs either on cell surfaces or in pla...

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Bibliographic Details
Main Authors: Kintzer, Alexander F., Sterling, Harry J., Tang, Iok I., Williams, Evan R., Krantz, Bryan A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975657/
https://ncbi.nlm.nih.gov/pubmed/21079738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013888
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