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Role of the protective antigen octamer in the molecular mechanism of anthrax lethal toxin stabilization in plasma
Anthrax is caused by strains of Bacillus anthracis that produce two key virulence factors, anthrax toxin (Atx) and a poly-γ-D-glutamic acid capsule. Atx is comprised of three-proteins: protective antigen (PA) and two enzymes, lethal factor (LF) and edema factor (EF). To disrupt cell function, these...
में बचाया:
मुख्य लेखकों: | , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
2010
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892534/ https://ncbi.nlm.nih.gov/pubmed/20433851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.041 |
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