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CCN2 Is Required for the TGF-β Induced Activation of Smad1 - Erk1/2 Signaling Network
Connective tissue growth factor (CCN2) is a multifunctional matricellular protein, which is frequently overexpressed during organ fibrosis. CCN2 is a mediator of the pro-fibrotic effects of TGF-β in cultured cells, but the specific function of CCN2 in the fibrotic process has not been elucidated. In...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3132735/ https://ncbi.nlm.nih.gov/pubmed/21760921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021911 |
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