11β-Hydroxysteroid Dehydrogenase Type 1 Deficiency Prevents Memory Deficits with Aging by Switching from Glucocorticoid Receptor to Mineralocorticoid Receptor-Mediated Cognitive Control

Local brain amplification of glucocorticoids (GCs) by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) plays a pivotal role in age-related memory deficits. 11β-HSD1 deficient mice are protected from spatial memory impairments with aging, but the underlying mechanisms are unknown. To determine whic...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Yau, Joyce L. W., Noble, June, Seckl, Jonathan R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132450/
https://ncbi.nlm.nih.gov/pubmed/21411659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6145-10.2011
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars