Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate

INTRODUCTION: Folate receptor (FR)-expressing macrophages have been shown to accumulate at sites of inflammation, where they promote development of inflammatory symptoms. To target such a macrophage population, we designed and evaluated the biologic activity of EC0746, a novel folic acid conjugate o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Lu, Yingjuan, Stinnette, Torian W, Westrick, Elaine, Klein, Patrick J, Gehrke, Mark A, Cross, Vicky A, Vlahov, Iontcho R, Low, Philip S, Leamon, Christopher P
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132048/
https://ncbi.nlm.nih.gov/pubmed/21463515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3304
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge