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Membrane folate-binding proteins are responsible for folate-protein conjugate endocytosis into cultured cells.

Folate-protein conjugates have been shown to bind to and enter HeLa and KB cells by receptor-mediated endocytosis [Leamon and Low (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 5572-5576]. Although these cells contain a membrane folate-binding protein (FBP) involved in the uptake of free folate, no studie...

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Bibliographic Details
Main Authors: Leamon, C P, Low, P S
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132447/
https://ncbi.nlm.nih.gov/pubmed/8387781
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