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Dendritic spine loss and neurodegeneration is rescued by Rab11 in models of Huntington's disease
Huntington's disease (HD) is a fatal neurodegenerative disorder caused by expansion of a polyglutamine tract in the huntingtin protein (htt) that mediates formation of intracellular protein aggregates. In the brains of HD patients and HD transgenic mice, accumulation of protein aggregates has b...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131896/ https://ncbi.nlm.nih.gov/pubmed/21217767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2010.127 |
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