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Slow protein evolutionary rates are dictated by surface–core association
Why do certain proteins evolve much slower than others? We compared not only rates per protein, but also rates per position within individual proteins. For ∼90% of proteins, the distribution of positional rates exhibits three peaks: a peak of slow evolving residues, with average log(2)[normalized ra...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131374/ https://ncbi.nlm.nih.gov/pubmed/21690394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015994108 |
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