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Slow protein evolutionary rates are dictated by surface–core association

Why do certain proteins evolve much slower than others? We compared not only rates per protein, but also rates per position within individual proteins. For ∼90% of proteins, the distribution of positional rates exhibits three peaks: a peak of slow evolving residues, with average log(2)[normalized ra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Tóth-Petróczy, Ágnes, Tawfik, Dan S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2011
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131374/
https://ncbi.nlm.nih.gov/pubmed/21690394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015994108
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