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Slow dimer dissociation of the TATA binding protein dictates the kinetics of DNA binding

The association of the TATA binding protein (TBP) to eukaryotic promoters is a possible rate-limiting step in gene expression. Slow promoter binding might be related to TBP’s ability to occlude its DNA binding domain through dimerization. Using a “pull-down” based assay, we find that TBP dimers diss...

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Detaylı Bibliyografya
Asıl Yazarlar: Coleman, Robert A., Pugh, B. Franklin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The National Academy of Sciences of the USA 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC23798/
https://ncbi.nlm.nih.gov/pubmed/9207072
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