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Slow protein evolutionary rates are dictated by surface–core association

Why do certain proteins evolve much slower than others? We compared not only rates per protein, but also rates per position within individual proteins. For ∼90% of proteins, the distribution of positional rates exhibits three peaks: a peak of slow evolving residues, with average log(2)[normalized ra...

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Detaylı Bibliyografya
Asıl Yazarlar: Tóth-Petróczy, Ágnes, Tawfik, Dan S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131374/
https://ncbi.nlm.nih.gov/pubmed/21690394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1015994108
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