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Metamorphic proteins mediate evolutionary transitions of structure

The primary sequence of proteins usually dictates a single tertiary and quaternary structure. However, certain proteins undergo reversible backbone rearrangements. Such metamorphic proteins provide a means of facilitating the evolution of new folds and architectures. However, because natural folds e...

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Hlavní autoři: Yadid, Itamar, Kirshenbaum, Noam, Sharon, Michal, Dym, Orly, Tawfik, Dan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867682/
https://ncbi.nlm.nih.gov/pubmed/20368465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912616107
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