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Mechanism and function of synaptotagmin-mediated membrane apposition

Synaptotagmin-I (syt) is a Ca(2+) sensor that triggers synchronous neurotransmitter release. The first documented biochemical property of syt was its ability to aggregate membranes in response to Ca(2+). However, the mechanism and function of syt-mediated membrane aggregation are poorly understood....

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Autori principali: Hui, Enfu, Gaffaney, Jon D., Wang, Zhao, Johnson, Colin P., Evans, Chantell S., Chapman, Edwin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130839/
https://ncbi.nlm.nih.gov/pubmed/21642967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2075
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