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Synaptotagmin-mediated bending of the target membrane is a critical step in Ca(2+)-regulated fusion

Decades ago it was proposed that exocytosis involves invagination of the target membrane, resulting in a highly localized site of contact between the bilayers destined to fuse. The vesicle protein synaptotagmin-I (syt) bends membranes in response to Ca(2+), but whether this drives localized invagina...

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Detalhes bibliográficos
Main Authors: Hui, Enfu, Johnson, Colin P., Yao, Jun, Dunning, F. Mark, Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758036/
https://ncbi.nlm.nih.gov/pubmed/19703397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.05.049
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