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mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation

We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of...

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Autori principali: Yu, James, Yaba, Aylin, Kasiman, Corinna, Thomson, Travis, Johnson, Joshua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130037/
https://ncbi.nlm.nih.gov/pubmed/21750711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021415
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