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The expanding role of mTOR in cancer cell growth and proliferation

The mechanistic/mammalian target of rapamycin (mTOR) is a conserved protein kinase that controls several anabolic processes required for cell growth and proliferation. As such, mTOR has been implicated in an increasing number of pathological conditions, including cancer, obesity, type 2 diabetes and...

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Detalhes bibliográficos
Publicado no:Mutagenesis
Main Authors: Cargnello, Marie, Tcherkezian, Joseph, Roux, Philippe P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5943824/
https://ncbi.nlm.nih.gov/pubmed/25688110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geu045
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