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mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation

We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of...

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Detalhes bibliográficos
Main Authors: Yu, James, Yaba, Aylin, Kasiman, Corinna, Thomson, Travis, Johnson, Joshua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130037/
https://ncbi.nlm.nih.gov/pubmed/21750711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021415
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