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mTOR Controls Ovarian Follicle Growth by Regulating Granulosa Cell Proliferation

We have shown that inhibition of mTOR in granulosa cells and ovarian follicles results in compromised granulosa proliferation and reduced follicle growth. Further analysis here using spontaneously immortalized rat granulosa cells has revealed that mTOR pathway activity is enhanced during M-phase of...

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Bibliografiske detaljer
Main Authors: Yu, James, Yaba, Aylin, Kasiman, Corinna, Thomson, Travis, Johnson, Joshua
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130037/
https://ncbi.nlm.nih.gov/pubmed/21750711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021415
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