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Enhancers of Adeno-associated Virus AAV2 Transduction via High Throughput siRNA Screening
Intracellular barriers to adeno-associated virus (AAV) transduction may limit gene delivery. We screened a short interfering RNA (siRNA) library targeting 5,520 genes to help identify pathways that modulate AAV transduction of human endothelium. In replicate screening, 50 pools (three siRNAs per gen...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129788/ https://ncbi.nlm.nih.gov/pubmed/21304495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.4 |
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