High-Throughput siRNA Screening to Reveal GATA-2 Upstream Transcriptional Mechanisms in Hematopoietic Cells

Hematopoietic stem cells can self-renew and differentiate into all blood cell types. The transcription factor GATA-2 is expressed in both hematopoietic stem and progenitor cells and is essential for cell proliferation, survival, and differentiation. Recently, evidence from studies of aplastic anemia...

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Pubblicato in:PLoS One
Autori principali: Saito, Yo, Fujiwara, Tohru, Ohashi, Keiichi, Okitsu, Yoko, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Harigae, Hideo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556642/
https://ncbi.nlm.nih.gov/pubmed/26325290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137079
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