Gene Expression Profiling Identifies HOXB4 as a Direct Downstream Target of GATA-2 in Human CD34+ Hematopoietic Cells

Aplastic anemia is characterized by a reduced hematopoietic stem cell number. Although GATA-2 expression was reported to be decreased in CD34-positive cells in aplastic anemia, many questions remain regarding the intrinsic characteristics of hematopoietic stem cells in this disease. In this study, w...

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Detalhes bibliográficos
Main Authors: Fujiwara, Tohru, Yokoyama, Hisayuki, Okitsu, Yoko, Kamata, Mayumi, Fukuhara, Noriko, Onishi, Yasushi, Fujimaki, Shinichi, Takahashi, Shinichiro, Ishizawa, Kenichi, Bresnick, Emery H., Harigae, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3454409/
https://ncbi.nlm.nih.gov/pubmed/23028422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040959
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