High-Throughput siRNA Screening to Reveal GATA-2 Upstream Transcriptional Mechanisms in Hematopoietic Cells

Hematopoietic stem cells can self-renew and differentiate into all blood cell types. The transcription factor GATA-2 is expressed in both hematopoietic stem and progenitor cells and is essential for cell proliferation, survival, and differentiation. Recently, evidence from studies of aplastic anemia...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Saito, Yo, Fujiwara, Tohru, Ohashi, Keiichi, Okitsu, Yoko, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Harigae, Hideo
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556642/
https://ncbi.nlm.nih.gov/pubmed/26325290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137079
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items