A Low-Molecular-Weight Compound K7174 Represses Hepcidin: Possible Therapeutic Strategy against Anemia of Chronic Disease

Hepcidin is the principal iron regulatory hormone, controlling the systemic absorption and remobilization of iron from intracellular stores. The expression of the hepcidin gene, HAMP, is increased in patients with anemia of chronic disease. Previously, the synthetic compound K7174 was identified thr...

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Detalhes bibliográficos
Main Authors: Fujiwara, Tohru, Ikeda, Takashi, Nagasaka, Yuki, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Tomosugi, Naohisa, Harigae, Hideo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785497/
https://ncbi.nlm.nih.gov/pubmed/24086573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075568
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