A Low-Molecular-Weight Compound K7174 Represses Hepcidin: Possible Therapeutic Strategy against Anemia of Chronic Disease

Hepcidin is the principal iron regulatory hormone, controlling the systemic absorption and remobilization of iron from intracellular stores. The expression of the hepcidin gene, HAMP, is increased in patients with anemia of chronic disease. Previously, the synthetic compound K7174 was identified thr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fujiwara, Tohru, Ikeda, Takashi, Nagasaka, Yuki, Okitsu, Yoko, Katsuoka, Yuna, Fukuhara, Noriko, Onishi, Yasushi, Ishizawa, Kenichi, Ichinohasama, Ryo, Tomosugi, Naohisa, Harigae, Hideo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785497/
https://ncbi.nlm.nih.gov/pubmed/24086573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075568
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