ROLE OF REACTIVE OXYGEN SPECIES DURING HYPERTENSION IN RESPONSE TO CHRONIC ANTI-ANGIOGENIC FACTOR (sFlt-1) EXCESS IN PREGNANT RATS

BACKGROUND: Preeclampsia is associated with increased levels of reactive oxygen species (ROS) and the anti-angiogenic factor, soluble fms-like tyrosine kinase (sFlt-1). Moreover, recent studies have indicated that chronic sFlt-1 excess causes hypertension in pregnant animals. The purpose of this stu...

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Hauptverfasser: Tam Tam, Kiran B., LaMarca, Babbette, Arany, Marietta, Cockrell, Kathy, Fournier, Lillian, Murphy, Sydney, Martin, James N., GRANGER, JOEY P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129783/
https://ncbi.nlm.nih.gov/pubmed/20725052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2010.180
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