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Control of soluble fms-like tyrosine-1 (sFlt-1) production response to placental ischemia/hypoxia: role of tumor necrosis factor-α

Although abnormal soluble fms-like tyrosine kinase-1 (sFlt-1) production is thought to be an important factor in the pathogenesis of preeclampsia (PE), the mechanisms that regulate the production of sFlt-1 during PE are unclear. While our laboratory has shown tumor necrosis factor-α (TNF-α) and sFlt...

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Detalhes bibliográficos
Main Authors: Murphy, Sydney R., LaMarca, B. Babbette D., Parrish, Marc, Cockrell, Kathy, Granger, Joey P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543655/
https://ncbi.nlm.nih.gov/pubmed/23193111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00069.2012
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