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Induction of heme oxygenase-1 attenuates sFlt-1-induced hypertension in pregnant rats

Preeclampsia (PE) is one of the leading causes of fetal and maternal morbidity, affecting 5–10% of all pregnancies, and lacks an effective treatment. The exact etiology of the disorder is unclear, but placental ischemia has been shown to be a central causative agent. In response to placental ischemi...

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Autores principales: George, Eric M., Arany, Marietta, Cockrell, Kathy, Storm, Megan V., Stec, David E., Granger, Joey P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213946/
https://ncbi.nlm.nih.gov/pubmed/21865547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00325.2011
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