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Induction of Heme Oxygenase-1 Attenuates Placental-Ischemia Induced Hypertension

Recent in vitro studies have reported that heme oxygenase-1 (HO-1) downregulates the angiostatic protein sFlt-1 from placental villous explants and that the HO-1 metabolites CO and bilirubin negatively regulates endothelin-1 and reactive oxygen species (ROS). Although sFlt-1, ET-1, and ROS have been...

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Detalhes bibliográficos
Main Authors: George, Eric M., Cockrell, Kathy, Aranay, Marietta, Csongradi, Eva, Stec, David E., Granger, Joey P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085942/
https://ncbi.nlm.nih.gov/pubmed/21383306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.111.169755
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