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Diacylglycerol kinase zeta deficiency in a non-CD4(+)T cell compartment leads to increased peanut hypersensitivity
Peanut sensitization in diacylglycerol kinase zeta (DGKζ) deficient mice led to elevated peanut-IgE levels and severe anaphylaxis. DGKζ deficient CD4(+)T cells did not account for the phenotype. Future studies will determine which immune lineage caused increased food hypersensitivity.
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129393/ https://ncbi.nlm.nih.gov/pubmed/21439625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.02.035 |
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