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Synergistic control of T cell development and tumor suppression by diacylglycerol kinase α and ζ
Diacylglycerol (DAG) kinases (DGKs) are a family of enzymes that convert DAG to phosphatidic acid (PA), the physiologic functions of which have been poorly defined. We report here that DGK α and ζ synergistically promote T cell maturation in the thymus. Absence of both DGKα and ζ (DGKα(−/−)ζ(−/−)) r...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575297/ https://ncbi.nlm.nih.gov/pubmed/18689679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711856105 |
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