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Type B CpG oligodeoxynucleotides induce Th1 responses to peanut antigens: modulation of sensitization and utility in a truncated immunotherapy regimen in mice

SCOPE: Peanut allergy stems from a Th2-biased immune response to peanut allergens leading to IgE production and allergic reactions upon ingestion. METHODS AND RESULTS: A model of peanut allergy in C3H/HeJ mice was used to assess whether Type A, B, or C CpG oligodeoxynucleotide (ODN) molecules would...

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Hlavní autoři: Kulis, Mike, Gorentla, Balachandra, Burks, A. Wesley, Zhong, Xiao-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810026/
https://ncbi.nlm.nih.gov/pubmed/23386314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201200410
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