Immunomodulatory Effects of CpG Oligodeoxynucleotides on Established Th2 Responses

CpG oligodeoxynucleotides (CpG ODNs) are known to induce type 1 T-helper-cell (Th1) responses. We have previously demonstrated that CpG ODNs administered during sensitization prevent Th2-mediated eosinophilic airway inflammation in vivo. We also reported that key Th1 cytokines, gamma interferon (IFN...

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Bibliografiske detaljer
Main Authors: Kitagaki, Kunihiko, Jain, Vipul V., Businga, Thomas R., Hussain, Iftikhar, Kline, Joel N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Immune-Mediated Responses and Disorders
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130087/
https://ncbi.nlm.nih.gov/pubmed/12414759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.6.1260-1269.2002
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