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Therapeutic Strategies for Targeting Ras Proteins

Ras genes are frequently activated in cancer. Attempts to develop drugs that target mutant Ras proteins have, so far, been unsuccessful. Tumors bearing these mutations, therefore, remain among the most difficult to treat. Most efforts to block activated Ras have focused on pathways downstream. Drugs...

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Bibliografske podrobnosti
Main Authors: Gysin, Stephan, Salt, Megan, Young, Amy, McCormick, Frank
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128641/
https://ncbi.nlm.nih.gov/pubmed/21779505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911412376
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