RAS Proteins and Their Regulators in Human Disease

RAS proteins are binary switches, cycling between ON and OFF states during signal transduction. These switches are normally tightly controlled, but in RAS-related diseases, such as cancer, RASopathies, and many psychiatric disorders, mutations in the RAS genes or their regulators render RAS proteins...

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Bibliographic Details
Published in:	Cell
Main Authors:	Simanshu, Dhirendra K., Nissley, Dwight V., McCormick, Frank
Format:	Artigo
Language:	Inglês
Published:	2017
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC5555610/ https://ncbi.nlm.nih.gov/pubmed/28666118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.009
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RAS Proteins and Their Regulators in Human Disease

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