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RAS Proteins and Their Regulators in Human Disease
RAS proteins are binary switches, cycling between ON and OFF states during signal transduction. These switches are normally tightly controlled, but in RAS-related diseases, such as cancer, RASopathies, and many psychiatric disorders, mutations in the RAS genes or their regulators render RAS proteins...
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| Publié dans: | Cell |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5555610/ https://ncbi.nlm.nih.gov/pubmed/28666118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.009 |
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