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RAS Proteins and Their Regulators in Human Disease

RAS proteins are binary switches, cycling between ON and OFF states during signal transduction. These switches are normally tightly controlled, but in RAS-related diseases, such as cancer, RASopathies, and many psychiatric disorders, mutations in the RAS genes or their regulators render RAS proteins...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Simanshu, Dhirendra K., Nissley, Dwight V., McCormick, Frank
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555610/
https://ncbi.nlm.nih.gov/pubmed/28666118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.009
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