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RAS Proteins and Their Regulators in Human Disease

RAS proteins are binary switches, cycling between ON and OFF states during signal transduction. These switches are normally tightly controlled, but in RAS-related diseases, such as cancer, RASopathies, and many psychiatric disorders, mutations in the RAS genes or their regulators render RAS proteins...

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Bibliografski detalji
Izdano u:Cell
Glavni autori: Simanshu, Dhirendra K., Nissley, Dwight V., McCormick, Frank
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555610/
https://ncbi.nlm.nih.gov/pubmed/28666118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.009
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