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ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications

For nearly a decade, the difficulties associated with both the determination and reproducibility of Ras-dependency indexes (RDIs) have limited their application and further delineation of the biology underlying Ras dependency. In this report, we describe the application of a computational single sam...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Yi, Ming, Nissley, Dwight V., McCormick, Frank, Stephens, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7314760/
https://ncbi.nlm.nih.gov/pubmed/32581224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66986-8
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