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Therapeutic Strategies for Targeting Ras Proteins

Ras genes are frequently activated in cancer. Attempts to develop drugs that target mutant Ras proteins have, so far, been unsuccessful. Tumors bearing these mutations, therefore, remain among the most difficult to treat. Most efforts to block activated Ras have focused on pathways downstream. Drugs...

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Detalhes bibliográficos
Main Authors: Gysin, Stephan, Salt, Megan, Young, Amy, McCormick, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128641/
https://ncbi.nlm.nih.gov/pubmed/21779505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911412376
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