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Rapid High Resolution Characterization of Functionally Important Monoclonal Antibody N-Glycans by Capillary Electrophoresis

Characterization of the N-glycosylation present in the Fc region of therapeutic monoclonal antibodies requires rapid, high resolution separation methods to guarantee product safety and efficacy during all stages of process development. Determination of fucosylated oligosaccharides is particularly im...

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Autori principali: Szabo, Zoltan, Guttman, András, Bones, Jonathan, Karger, Barry L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128192/
https://ncbi.nlm.nih.gov/pubmed/21591710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac2007587
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