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Rapid High Resolution Characterization of Functionally Important Monoclonal Antibody N-Glycans by Capillary Electrophoresis

Characterization of the N-glycosylation present in the Fc region of therapeutic monoclonal antibodies requires rapid, high resolution separation methods to guarantee product safety and efficacy during all stages of process development. Determination of fucosylated oligosaccharides is particularly im...

詳細記述

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書誌詳細
主要な著者: Szabo, Zoltan, Guttman, András, Bones, Jonathan, Karger, Barry L.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128192/
https://ncbi.nlm.nih.gov/pubmed/21591710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac2007587
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