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Ultrasensitive Capillary Electrophoretic Analysis of Potentially Immunogenic Carbohydrate Residues in Biologics: Galactose-α-1,3-Galactose Containing Oligosaccharides

With the recent growth of the global monoclonal antibody market, ultrasensitive techniques are required for rapid analysis of possible immunogenic residues, such as galactose-α-1,3-galactose (α-1,3-Gal) on therapeutic proteins expressed in murine or CHO cell lines. We report a capillary electrophore...

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Autors principals: Szabo, Zoltan, Guttman, Andras, Bones, Jonathan, Shand, Randi L., Meh, David, Karger, Barry L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367134/
https://ncbi.nlm.nih.gov/pubmed/22571495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp200612n
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