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Sialic Acid Speciation using Capillary Electrophoresis: Optimization of Analyte Derivatization and Separation

Capillary electrophoresis with laser induced fluorescence detection (CE-LIF) was employed for rapid sialic acid speciation, facilitating the quantitative determination of N-glycolylneuraminic acid (Neu5Gc) and N-acetylneuraminic acid (Neu5Ac) on glycoproteins. Derivatization of the sialic acids with...

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Detalhes bibliográficos
Main Authors: Szabo, Zoltan, Bones, Jonathan, Guttman, Andras, Glick, James, Karger, Barry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445727/
https://ncbi.nlm.nih.gov/pubmed/22901108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac301840f
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