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Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
The Ddc1/Rad17/Mec3 complex and Rad24 are DNA damage checkpoint components with limited homology to replication factors PCNA and RF-C, respectively, suggesting that these factors promote checkpoint activation by “sensing” DNA damage directly. Mec1 kinase, however, phosphorylates the checkpoint prote...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC312815/ https://ncbi.nlm.nih.gov/pubmed/11691833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.903501 |
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