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DJ-1 regulation of mitochondrial function and autophagy through oxidative stress

The dysregulation of mitochondrial function has been implicated in the pathogenesis of Parkinson disease. Mutations in the parkin, PINK1 and DJ-1 genes all result in recessive parkinsonism. Although the protein products of these genes have not been fully characterized, it has been established that a...

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Main Authors: McCoy, Melissa K, Cookson, Mark R
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127213/
https://ncbi.nlm.nih.gov/pubmed/21317550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.5.14684
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