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Mitochondrial oxidative stress mediates induction of autophagy and hypertrophy in angiotensin-II treated mouse hearts

Autophagy is characterized by recycling of cellular organelles and can be induced by several stimuli, including nutrient deprivation and oxidative stress. As a major site of free radical production during oxidative phosphorylation, mitochondria are believed to be primary targets of oxidative damage...

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Autors principals: Dai, Dao-Fu, Rabinovitch, Peter
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359471/
https://ncbi.nlm.nih.gov/pubmed/21505274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.8.15813
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